News: Personalized Oncology

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Cancer Survivors’ Day Highlights

Tuesday, June 21st, 2011

More than 350 cancer survivors, caregivers, advocates and health professionals gathered at the Vanderbilt Student Life Center last Saturday (June 18, 2011) to learn, connect and celebrate. Cancer GPS: Navigating Your Journey included remarks from keynote speaker Linda Armstrong Kelly (author and mother of champion cyclist and survivor Lance Armstrong), music and stories from survivor, […]

VUMC Debuts New DNA Sequencers

Monday, May 2nd, 2011

Since the first of the year, one cutting-edge sequencer, the Illumina HiSeq 2000, has been installed in a lab in the Preston Research Building, and another has been delivered. More than 30 Vanderbilt investigators have submitted samples for sequencing by the machines, which are not much bigger than half-size refrigerators.“The access to this technology allows […]

Experts Explore Gene Testing Effects

Friday, April 1st, 2011

A mere 10 years after the first draft of the human genome sequence was completed, scientists and companies are delivering some of the first fruits of that achievement to patients and consumers. At Vanderbilt University Medical Center, for example, patients scheduled for cardiac catheterization are tested for a genetic variation to determine which blood thinner […]

VICC Launches Genetic Research Tool

Friday, March 4th, 2011

Vanderbilt-Ingram Cancer Center has launched the nation’s first personalized cancer decision support tool, “My Cancer Genome,” to help physicians and researchers track the latest developments in personalized cancer medicine and connect with clinical research trials for their patients. This web-based information tool is designed to quickly educate clinicians on the rapidly expanding list of genetic […]

VICC’s Lovly Receives Lung Cancer Grant

Friday, February 4th, 2011

Uniting Against Lung Cancer, a nonprofit organization dedicated to funding innovative lung cancer research in the United States and Canada, has awarded a $100,000 grant to Christine Lovly, M.D., Ph.D., a fellow in the Division of Hematology/Oncology at Vanderbilt-Ingram Cancer Center. The two-year grant will fund Lovly’s research on better treatment options for a subset […]

Drug Gets ‘Personal’ With Lung Cancer

Friday, January 7th, 2011

Paula Hart was just 46 when she starting having shortness of breath, along with a nagging cough and intermittent pain in her left shoulder. After a trip to the emergency room in her hometown of Evansville, Ind., and a series of additional tests, doctors finally diagnosed Hart with non-small cell lung cancer. The cancer was […]

Clinical Trials in Era of Targeted Therapies

Friday, December 17th, 2010

Cousins with melanoma caused by the same genetic mutation enroll in a randomized clinical trial of a promising experimental drug that targets the mutation. Randomly assigned to different groups, one young man gets the new drug, experiences dramatic shrinkage of his tumors and is alive nine months later, while his cousin receives current therapy — […]

Clue to Melanoma Drug Resistance

Friday, December 17th, 2010

Patients with metastatic melanoma being treated with the new investigational cancer drug PLX4032 are showing strong responses, with an 80 percent anti-tumor response rate among patients whose tumors are positive for the B-RAF (V600E) gene mutation. However, in all too many cases, patients are developing resistance to the drug and their cancer is beginning to […]

DNA Mechanics

Wednesday, December 8th, 2010

Picture a railroad track, running across the countryside. DNA looks something like that track. Its “rails” are chains of chemicals called nucleotides, each pairing with a partner on the opposite chain to form the “ties.” To ensure timely train traffic – and prevent catastrophic derailments – the railroad track needs regular maintenance. So does DNA. […]

Cancer Care Gets Personal

Wednesday, December 8th, 2010

Vanderbilt-Ingram Cancer Center has become the first cancer center in the Southeast and one of the first in the nation to offer adult cancer patients routine “genotyping” of their tumors at the DNA level. The recently launched Personalized Cancer Medicine Initiative will personalize cancer treatment by matching the appropriate therapy to the genetic changes, or […]