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Lung Cancer Mutations Suggest New Therapies

Tuesday, July 31st, 2012

Vanderbilt-Ingram Cancer Center researchers have identified how one of the genes most commonly mutated in lung cancer may promote such tumors. The investigators found that the protein encoded by this gene, called EPHA3, normally inhibits tumor formation, and that loss or mutation of the gene – as often happens in lung cancer – diminishes this […]

Study Finds Stress Fuels Breast Cancer Metastasis to Bone

Wednesday, July 18th, 2012

Stress can promote breast cancer cell colonization of bone, Vanderbilt Center for Bone Biology investigators have discovered. The studies, reported July 17 in PLoS Biology, demonstrate in mice that activation of the sympathetic nervous system – the “fight-or-flight” response to stress – primes the bone environment for breast cancer cell metastasis. The researchers were able […]

Preston Left Enduring Legacy

Friday, June 22nd, 2012

Members of the Vanderbilt community have spent the past week sharing remembrances of a Nashville businesswoman who made an indelible mark on the Medical Center. Frances Williams Preston, one of the most successful female executives in the music industry and a member of the Vanderbilt-Ingram Cancer Center Board of Overseers, passed away at her Nashville […]

Vanderbilt Mourns Loss of Frances Williams Preston

Friday, June 15th, 2012

Frances Williams Preston, one of the most successful female music executives in the history of the entertainment industry, and a member of the Vanderbilt-Ingram Cancer Center Board of Overseers, died from congestive heart failure at her home in Nashville, surrounded by her family, Wednesday, June 13. She was 83. Mrs. Preston spent most of her […]

Patient Lauded for Clinical Trial Participation

Wednesday, June 13th, 2012

A breast cancer patient who has enrolled in two clinical research trials at Vanderbilt-Ingram Cancer Center was the only presenter to receive a standing ovation during a recent Stand Up To Cancer (SU2C) news briefing at the American Association for Cancer Research (AACR) annual meeting in Chicago. Jeanette Daniel, 51, a metastatic breast cancer patient, […]

Open House Slated for TPSR

Thursday, May 24th, 2012

The Translational Pathology Shared Resource (TPSR) has opened an expanded laboratory on the first floor of Medical Center North, room S-1310. To celebrate the grand opening of the newly renovated space, TPSR is hosting an open house on Wednesday, May 30, from 1-3 p.m. Vanderbilt faculty and staff are invited to tour the new space, […]

Free Screening for Head and Neck Cancer

Friday, April 20th, 2012

The symptoms of head and neck cancer can be subtle, so to help catch the disease in its earliest stages the Tennessee Chapter of the Head and Neck Cancer Alliance, Vanderbilt-Ingram Cancer Center, the Vanderbilt Bill Wilkerson Center for Otolaryngology and Communication Sciences, Meharry Medical College and the VA Tennessee Valley Healthcare System will offer […]

Investigators Win Global GE Research Grants

Tuesday, March 27th, 2012

Vanderbilt-Ingram Cancer Center investigators have won two of the five global innovation grants awarded by the “GE Healthymagination Cancer Challenge.” The grants were awarded to Jennifer Pietenpol, Ph.D., director of VICC, and the My Cancer Genome project, developed by Mia Levy, M.D., Ph.D., assistant professor of Medicine and Biomedical Informatics, and William Pao, M.D., Ph.D., […]

Lung Cancer Screening Trial Helps First Patient

Friday, March 2nd, 2012

Kathy Leiser first heard about Vanderbilt-Ingram Cancer Center’s lung cancer screening trial through a sponsorship ad on WPLN radio last summer. The Nashville office technology saleswoman and grandmother of three had stopped smoking in 2009, but she knew her smoking history put her at risk for lung cancer. So she enrolled in the screening trial, […]

Colorectal Cancer Risk Related to Gene’s Expression

Friday, January 27th, 2012

Individuals who are outside the “normal” range of expression for the APC gene have an increased risk of colorectal cancer, according to a study published in the January issue of Gastroenterology. Mutations in the APC (adenomatous polyposis coli) gene – and variations in the expression of the gene’s two copies (allele-specific expression) — are associated […]