News: Clinical Trials

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Drug Gets ‘Personal’ With Lung Cancer

Friday, January 7th, 2011

Paula Hart was just 46 when she starting having shortness of breath, along with a nagging cough and intermittent pain in her left shoulder. After a trip to the emergency room in her hometown of Evansville, Ind., and a series of additional tests, doctors finally diagnosed Hart with non-small cell lung cancer. The cancer was […]

Share Your Stories, Art

Wednesday, January 5th, 2011

Tabula Rasa, the School of Medicine’s journal of medical humanities, is now accepting submissions for its 2010-2011 issue. The theme of this year’s journal is “Transformation: How Illness and Healing Change Us.” All submissions that meet the criteria (see below) will be featured on the Tabula Rasa website, and many of the selected submissions will […]

Call Center Operations Restored

Tuesday, January 4th, 2011

Update as of Thursday, Jan. 6: Call Center staff have been relocated to temporary locations, with phones and computers, so our service has been restored. Thanks to everyone for their patience while we addressed this unexpected situation. Kudos to our team for their dedication to finding a way to get back on line for our […]

New Online Community for Survivors

Friday, December 31st, 2010

Editor’s note: Cynthia Floyd Manley, Vanderbilt-Ingram Cancer Center’s associate director for communications, will appear on Lifetime Television’s The Balancing Act on Monday, Jan. 3, to discuss social networking for cancer survivors and caregivers. Vanderbilt-Ingram Cancer Center has joined with the national CancerConnect.com initiative to launch a new online community for people impacted by cancer. As […]

Clinical Trials in Era of Targeted Therapies

Friday, December 17th, 2010

Cousins with melanoma caused by the same genetic mutation enroll in a randomized clinical trial of a promising experimental drug that targets the mutation. Randomly assigned to different groups, one young man gets the new drug, experiences dramatic shrinkage of his tumors and is alive nine months later, while his cousin receives current therapy — […]

Clue to Melanoma Drug Resistance

Friday, December 17th, 2010

Patients with metastatic melanoma being treated with the new investigational cancer drug PLX4032 are showing strong responses, with an 80 percent anti-tumor response rate among patients whose tumors are positive for the B-RAF (V600E) gene mutation. However, in all too many cases, patients are developing resistance to the drug and their cancer is beginning to […]

Oncology Clinic Takes Magnet to Heart

Friday, November 19th, 2010

Vanderbilt-Ingram Cancer Center’s Oncology Clinic in Cool Springs makes patient care its priority, and provides a strong example of why the Medical Center is deserving of a second Magnet designation. Though the clinic is 16 miles from the main Vanderbilt University Medical Center campus, the culture of this suburban clinic embodies the VUMC Nursing philosophy […]

New Melanoma Therapy Shows Promise

Friday, November 12th, 2010

A clinical trial of a new experimental therapy for metastatic melanoma being tested at Vanderbilt and several other medical centers has shown positive results, including tumor shrinkage in the majority of patients. The results support previously reported positive data for the drug, known as PLX4032 (RG7204), in a much larger patient population where all responses […]

VUMC Joins Blood-Brain Barrier Group

Friday, November 12th, 2010

Vanderbilt University Medical Center has joined the International Blood-Brain Barrier Consortium, a group that is combining research and comprehensive patient care to develop protocols and guidelines for opening the blood-brain barrier. The blood-brain barrier is a system of tight junctions in the circulatory system around the brain that protects the central nervous system from unsafe […]

Grants to Fund Research on Early Detection

Thursday, November 4th, 2010

The National Cancer Institute has awarded two Early Detection Research Network (EDRN) grants to a group of Vanderbilt-Ingram Cancer Center investigators to support early detection of lung and colon cancers. Pierre Massion, M.D., associate professor of Medicine and Cancer Biology, has been awarded $3 million over five years for the creation of the Vanderbilt Clinical […]